Stage 4 triple negative breast cancer

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A native of Colorado, this adventurous spirit moved with her husband to Alaska where they served at the Skwentna checkpoint for the Iditarod competition held each year. Cyndy's saga began in when she underwent surgery for triple negative breast cancer and 4 of 18 lymph nodes were positive. She received radiation to avoid recurrence.

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Give us feedback! Take our podcast listener survey. Two cases of possible remission in metastatic triple-negative breast cancer [published online first September 28, ].

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The prognosis of triple-negative breast cancer with metastases after chemotherapy remains dismal. We report the case of a year-old female with first disease recurrence at the axillary lymph node and, later on, bilateral pulmonary metastases with severe shortness of breath. The patient received low-dose immune checkpoint blockade concurrent nivolumab and ipilimumab weekly over 3 weeks with regional hyperthermia 3 times a week, followed by systemic fever-range hyperthermia induced by interleukin-2 for 5 days.

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Metrics details. Several accomplishments have been achieved in triple-negative breast cancer TNBC research over the last year. The phase III IMpassion trial comparing chemotherapy plus atezolizumab versus chemotherapy plus placebo brought breast cancer into the immunotherapy era.

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Some questions you may have are:. The answer to those and other questions you have will depend on a lot of factors, such as the stage of the cancer and how well it responds to treatment. Keep reading to learn more about TNBC and your outlook.

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Triple-negative breast cancer is an aggressive form of the disease. To understand it, a person should know about the other types of breast cancer. Some breast cancers have receptor cells that respond to hormones.

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Triple-negative breast cancer is cancer that tests negative for estrogen receptors, progesterone receptors, and excess HER2 protein. These results mean the growth of the cancer is not fueled by the hormones estrogen and progesterone, or by the HER2 protein. So, triple-negative breast cancer does not respond to hormonal therapy medicines or medicines that target HER2 protein receptors.

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Most women with stage IV breast cancer are mainly treated with systemic therapy. This may include hormone therapy, chemotherapy, targeted therapy, or some combination of these. Local treatments such as surgery or radiation might also be used to help prevent or treat symptoms.

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This means that the breast cancer cells have tested negative for hormone epidermal growth factor receptor 2 HER-2estrogen receptors ERand progesterone receptors PR. In fact, triple negative breast cancer may respond even better to chemotherapy in the earlier stages than many other forms of cancer. Triple negative breast cancer can be more aggressive and difficult to treat. Also, the cancer is more likely to spread and recur.

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